Effect of Schistosoma haematobium infection on the cognitive functions of preschool age children and benefits of treatment from an endemic area in Zimbabwe

Abstract Background Floor Care Concrete Schistosomiasis is known to affect the cognitive functions of children, however, but there is paucity of information on its impact on early childhood development in developing countries where the disease is endemic.This study aimed at determining the effects of schistosomiasis due to Schistosoma haematobium o

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An Increase in Mesenchymal Stem Cells Expressing Nestin in Bone-Marrow-Derived Primary Cells Stimulates Neurogenic Differentiation in Rat

Mesenchymal stem cells Pls LEd (MSCs) have been considered an alternative source of neuronal lineage cells, which are difficult to isolate from brain and expand in vitro.Previous studies have reported that MSCs expressing Nestin (Nestin+ MSCs), a neuronal stem/progenitor cell marker, exhibit increased transcriptional levels of neural development-re

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Manipulating heat shock factor-1 in Xenopus tadpoles: neuronal tissues are refractory to exogenous expression.

BACKGROUND: The aging related decline of heat shock factor-1 (HSF1) signaling may be causally related to protein aggregation diseases.To model such disease, we tried to cripple HSF1 signaling in the Xenopus tadpole.RESULTS: Over-expression of heat shock factor binding protein-1 did not inhibit the heat shock response in Xenopus.RNAi against HSF1 mR

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